Tesorai Search
More confident identifications from raw mass spectrometry data
Tesorai Search processes DDA and DIA proteomics data at scale, identifying more high-confidence peptides and proteins without sacrificing sensitivity.
Why Tesorai Search
Why teams choose Tesorai
More peptides, less time, at any scale, validated in independent benchmarks and published research.
How it works
From raw files to confident results
Tesorai Search brings the essential steps of proteomics search into one scalable workflow, without requiring researchers to assemble and maintain their own compute pipeline.
01
Upload raw data
Start with DDA or DIA mass spectrometry files.
02
Configure your search
Select the relevant database, modifications, and search parameters.
03
Process at scale
Run datasets ranging from individual experiments to thousands of files.
04
Review and export
Examine peptide and protein identifications and download the results.
Accuracy
Up to 10x improvement in identification accuracy, with no loss in sensitivity
In an independent entrapment analysis with a biotech partner, Tesorai Search returned 10x fewer false identifications than another leading search engine at the same reported 1% FDR, while identifying a comparable number of true peptides. Entrapment analyses append sequences known not to be present in the sample; any “identification” matching one of these sequences is a guaranteed false positive, giving an independent check on whether a tool's reported error rate can be trusted.
Up to 10×
improvement in identification accuracy
No loss in sensitivity
Sensitivity
Up to 68% more peptides than leading search engines
Independent benchmarks show up to 68% more peptide identifications than four leading proteomics search engines at the same 1% FDR.
Up to 68%
more peptides identified
Best observed benchmark; leading search engine indexed to 100
Higher peptide identifications across four benchmark comparisons
Read the peer-reviewed study →Speed
Process data in a fraction of the time
As both file size and dataset volume grow, Tesorai Search delivers rapid, scalable performance across even the most complex workloads.
200+ files processed in under an hour - built for speed at scale
2,500 immunopeptidomics files processed in under 5 hours, compared with more than 8 weeks using the previous workflow
Handles massive files with ease - proven on large datasets (e.g., Astral files)
>8 weeks
traditional pipeline
→
<5 hrs
Tesorai Search
2,500 immunopeptidomics files
Start a job
Job name
Experimental Design
+ Add
0 files added
FASTA files
Select
⌄
Parameters
︿
Acquisition mode:
⌄
Digestion enzyme:
TRYPSIN_P
⌄
Post processing FDR threshold:
expected level of false positives in final results
1
%
Browser-based workflow
Powerful search, without managing infrastructure
Set up, run, and review proteomics searches in your browser while Tesorai handles the underlying compute infrastructure.
No software installation or local compute setup
A guided interface for experimental design and search parameters
Compute that scales from individual experiments to thousands of files
Results that move directly into Tesorai Chat for downstream analysis
Real results
More findings. Greater accuracy. Less waiting.
10×
improvement in identification accuracy
Up to 68%
more peptides identified than leading search engines
<5 hours
to process 2,500 immunopeptidomics files
Results vary by dataset and search configuration.
Start unlocking the power of Tesorai
Get in touch and see what Tesorai can do with your data
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Insights leveraging every byte of raw data